please refer also to the German & other pages, as most sections are in English


NEU/New February 2018: Download Forms & Algorithms !

IRB approval pending, expected soon

registry within www.clinicaltrials.gov planned




Severe Immune Cytopenia registry | SIC-reg.org

Chronic Immune Thrombocytopenia (ITP) | Autoimmune Hemolytic Anemia (AIHA) | Evans Syndrome (ES)


Research for underlying causes
and treatment optimization

Multicenter
observational study

Treatment according to
international guidelines



Primary Immune Deficiencies

... involve a 120-fold (60-830x) increased risk for immune cytopenia
(Fischer et al., JACI 2017)

Bone marrow failure

... may initially present like immune cytopenia and may arise from immunologically mediated destruction of hematopoietic stem cells

Secondary cytopenias

... are caused by an array of different causes including infections or drugs in individuals with often unknown preexisting risk factors